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   Inert Complex
   Activated Monomer
   Active Dimer
   DNA-Bound
   Induction of Transcription


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activated monomer

Formation of the Activated Monomer

After administering the steroid, the steroid binds to the ligand binding domain of the monomer (PR). This causes a conformational change in the monomeric polypeptide's structure, and leads to the release of the Hsp and accessory proteins.